NAD+ FORMULA.
Featuring Nicotinamide Adenine Dinucleotide, a coenzyme included to complement a forward-thinking multivitamin routine.
COMPLETE B-COMPLEX.
A full spectrum of B vitamins, including methylated B12, folate, and active B6 (P5P), thoughtfully selected for daily balance.
BIOTIN & ALPHA LIPOIC ACID.
5,000 mcg of biotin paired with alpha lipoic acid—two essentials woven into a modern micronutrient blend.
Multivitamin with NAD+
Codeage Multivitamin NAD combines Nicotinamide Adenine Dinucleotide (NAD+) with a full-spectrum multivitamin profile. It includes vitamins A, C, D3, E, K2, and active forms of B vitamins such as methylated B12, folate, and P5P.*
More Than One Vitamin: The B-Complex Family
The B vitamins are a group of eight individual nutrients, each with a unique name and structure. These include:
- B1 (thiamin)
- B2 (riboflavin)
- B3 (niacin)
- B5 (pantothenic acid)
- B6 (pyridoxine)
- B7 (biotin)
- B9 (folate)
- B12 (cobalamin)
Though each of these vitamins has its own history and identity, they are commonly found together—both in food sources and supplement routines—because they often work in coordination within the body. Their natural synergy makes them a frequent combination in blends that support a variety of daily wellness goals, including those related to skin, energy, and cellular systems.*
Riboflavin: A Distinct Member of the Group
Riboflavin (B2) has a natural bright yellow pigment that gives many multivitamins and powders their golden or fluorescent hue. Though subtle, it plays an important role in skin-focused formulas and is often combined with biotin, niacinamide, and pantothenic acid to highlight B-vitamin synergy.
Niacinamide (B3), widely known in skincare, also appears in supplements for its role in the B-complex family. Its compatibility with riboflavin and pantothenic acid makes it a key ingredient in inner beauty routines.
Nutrients That Complement Each Other
Skin-focused supplements that include B-complex blends are often designed to align with broader routines, which can be layered with zinc, vitamin C, ceramides, or plant extracts that complement their presence.
The consistent inclusion of B vitamins in skin-targeted formulations isn't just about individual activity—it's about supporting a nutrient system that operates best when it works in concert. Riboflavin, as part of that system, helps complete that picture.
As always, talk to your doctor before taking any supplements. Get professional advice if you think you might need any riboflavin supplement or are already taking one to ensure you’re not exceeding the amounts you may need.
Historical overview
Nicotinamide Riboside (NR) might not be a household name, but this unique form of vitamin B3 has been stirring up excitement in the scientific community since its discovery in the early 21st century. Initially, NR was identified as a nutrient in milk, but it was only in 2004 that Dr. Charles Brenner discovered its potential role as a precursor to Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme found in all living cells which may play a role in numerous biological processes.
The biology and chemistry of nicotinamide riboside
Nicotinamide Riboside (NR) is a natural form of vitamin B3 and a precursor to NAD+. Once consumed, NR is thought to convert into NAD+, a molecule essential for energy metabolism and cellular function.* NAD+ participates in redox reactions, supporting metabolism by transferring electrons, and also serves as a substrate for enzymes like sirtuins and PARPs, which may influence DNA repair, stress response, and aging.* However, NAD+ levels naturally decline with age, potentially affecting cell function.* Chemically, NR is a pyridine-nucleoside similar to nicotinamide but with an added ribose sugar, which may allow a distinct pathway for conversion into NAD+.
NR+ supplements
Given the potential role of NAD+ and the fact that its levels could decline with age, scientists have been exploring ways to boost NAD+ levels in the body. That's where NR supplements, often labeled as "NR+", come in.
NR+ supplements contain NR, which might be converted into NAD+ once ingested, potentially supporting NAD+ levels and sirtuin activity.* Research suggests that boosting NAD+ levels might have several health benefits, including supporting energy metabolism, brain function, and potential healthy aging in certain populations.
However, while early research is promising, it's essential to note that much of the research to date has been conducted in mammals. More research, particularly large-scale human trials, is needed to continue understanding its role. You might also want to read about pterostilbene.
Interesting facts about nicotinamide riboside
- Found in Milk: NR was first identified as a trace nutrient in milk. However, you would need to consume impractical amounts of milk to get a significant dose of NR.
- NAD+ Precursor: NR is seen as potentially more efficient at raising NAD+ levels in the body compared to other forms of vitamin B3, like niacin and nicotinamide in certain populations.*
- Exercise and heart health: Studies in mice suggest that NR supplementation may help support exercise endurance and heart health, but these findings need to be confirmed in humans.
- Safety profile: NR is generally well-tolerated, with few side effects. However, as with all supplements, it's recommended to consult with a healthcare provider before starting.